Richard E Pratley Selected Research

Sitagliptin Phosphate (Januvia)

4/2021	Oral Semaglutide Reduces HbA1c and Body Weight in Patients with Type 2 Diabetes Regardless of Background Glucose-Lowering Medication: PIONEER Subgroup Analyses.
1/2018	Ertugliflozin plus sitagliptin versus either individual agent over 52 weeks in patients with type 2 diabetes mellitus inadequately controlled with metformin: The VERTIS FACTORIAL randomized trial.
1/2013	Liraglutide achieves A1C targets more often than sitagliptin or exenatide when added to metformin in patients with type 2 diabetes and a baseline A1C <8.0%.
10/2012	Efficacy and safety of switching from the DPP-4 inhibitor sitagliptin to the human GLP-1 analog liraglutide after 52 weeks in metformin-treated patients with type 2 diabetes: a randomized, open-label trial.
4/2010	Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial.
6/2007	Does addition of sitagliptin to metformin monotherapy improve glycemic control in patients with type 2 diabetes mellitus?

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Richard E Pratley Research Topics

Disease

98	Type 2 Diabetes Mellitus (MODY) 02/2024 - 02/2002
31	Insulin Resistance 01/2022 - 03/2002
24	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2024 - 04/2015
23	Hypoglycemia (Reactive Hypoglycemia) 10/2023 - 04/2007
21	Obesity 05/2023 - 03/2002
19	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 02/2005
19	Body Weight (Weight, Body) 01/2024 - 01/2008
14	Myocardial Infarction 01/2023 - 07/2006
13	Stroke (Strokes) 01/2023 - 07/2016
13	Hyperglycemia 01/2020 - 04/2007
12	Weight Loss (Weight Reduction) 01/2023 - 01/2008
12	Inflammation (Inflammations) 11/2018 - 02/2002
10	Heart Failure 10/2023 - 09/2006
9	Prediabetic State (Prediabetes) 01/2023 - 02/2010
8	Chronic Renal Insufficiency 01/2024 - 01/2018
7	Overweight 01/2023 - 01/2018
5	Kidney Diseases (Kidney Disease) 01/2024 - 01/2014
5	Weight Gain 01/2021 - 04/2011
4	Glucose Intolerance 12/2021 - 06/2002
3	Diabetes Mellitus 01/2023 - 11/2017
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2023 - 02/2008
3	Fibrosis (Cirrhosis) 01/2023 - 09/2006
3	Pancreatitis 01/2022 - 10/2021
3	Asthma (Bronchial Asthma) 10/2012 - 09/2010
2	COVID-19 03/2023 - 11/2022
2	Non-alcoholic Fatty Liver Disease 01/2023 - 01/2023
2	Albuminuria 08/2022 - 01/2021
2	Neoplasms (Cancer) 01/2022 - 01/2018
2	Body Weight Changes 04/2021 - 12/2011
2	Frailty 01/2020 - 01/2014
2	Ischemic Stroke 01/2019 - 10/2016
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2017 - 10/2016
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2016 - 01/2016
2	Alzheimer Disease (Alzheimer's Disease) 01/2016 - 01/2012
1	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 03/2024

Drug/Important Bio-Agent (IBA)

43	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 06/2002
39	Insulin (Novolin)FDA Link 03/2024 - 02/2002
21	Liraglutide FDA Link 08/2021 - 04/2010
17	Glucagon-Like Peptide-1 Receptor AgonistsIBA 02/2024 - 01/2008
16	Glucagon-Like Peptide 1 (GLP 1)IBA 10/2022 - 01/2008
12	ertugliflozinIBA 10/2023 - 01/2018
11	semaglutideIBA 01/2023 - 01/2018
11	Insulin Glargine (Lantus)FDA Link 11/2021 - 09/2016
11	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2020 - 04/2007
10	omega-Chloroacetophenone (Mace)IBA 01/2023 - 01/2018
10	insulin degludecIBA 11/2021 - 09/2016
10	IncretinsIBA 01/2020 - 04/2007
9	Biomarkers (Surrogate Marker)IBA 10/2023 - 02/2005
9	Metformin (Glucophage)FDA LinkGeneric 04/2021 - 06/2007
8	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020 - 04/2007
7	Glucagon-Like Peptide-1 ReceptorIBA 02/2024 - 07/2017
7	Peptides (Polypeptides)IBA 10/2022 - 01/2009
7	Pioglitazone (Actos)FDA Link 01/2022 - 02/2006
6	Vitamin D FDA LinkGeneric 02/2024 - 11/2017
6	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 07/2023 - 12/2011
6	Proteins (Proteins, Gene)FDA Link 03/2023 - 06/2002
6	Sitagliptin Phosphate (Januvia)FDA Link 04/2021 - 06/2007
5	CreatinineIBA 10/2023 - 01/2020
4	LipidsIBA 01/2024 - 01/2018
4	Blood Glucose (Blood Sugar)IBA 01/2023 - 01/2009
4	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022 - 07/2017
4	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2016
4	Hemoglobins (Hemoglobin)IBA 11/2021 - 01/2018
4	dulaglutideIBA 11/2021 - 01/2018
4	Hormones (Hormone)IBA 01/2020 - 01/2008
4	AdipokinesIBA 07/2016 - 06/2011
4	AdiponectinIBA 10/2012 - 06/2002
3	SodiumIBA 01/2024 - 01/2022
3	C-PeptideIBA 01/2023 - 04/2016
3	Sodium-Glucose Transport ProteinsIBA 01/2023 - 07/2017
3	Volatile Fatty AcidsIBA 01/2023 - 11/2022
3	Exenatide (Byetta)FDA Link 10/2021 - 01/2008
3	SugarsIBA 11/2018 - 03/2004
3	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 07/2017 - 01/2009
3	CytokinesIBA 10/2012 - 02/2005
3	Amyloid (Amyloid Fibrils)IBA 01/2012 - 07/2008
3	alogliptinIBA 11/2009 - 02/2009
2	rGLP-1 proteinIBA 02/2024 - 04/2014
2	AlbuminsIBA 10/2023 - 01/2020
2	CarbohydratesIBA 01/2023 - 01/2023
2	efpeglenatideIBA 01/2022 - 11/2019
2	Cholecalciferol (Vitamin D3)FDA Link 01/2022 - 11/2017
2	SaccharinIBA 12/2021 - 01/2017
2	glimepiride (Amarel)FDA LinkGeneric 01/2021 - 04/2016
2	LinagliptinIBA 01/2021 - 01/2014
2	Protein Isoforms (Isoforms)IBA 01/2017 - 01/2012
2	Insulin ReceptorIBA 01/2016 - 06/2002
2	ThiazolidinedionesIBA 01/2014 - 02/2009
2	LeptinIBA 10/2012 - 03/2011
2	VildagliptinIBA 01/2009 - 12/2007
2	Interleukin-6 (Interleukin 6)IBA 07/2008 - 02/2005
2	Plasminogen InactivatorsIBA 09/2006 - 07/2006
2	Plasminogen Activator Inhibitor 1IBA 09/2006 - 07/2006

Therapy/Procedure

26	Therapeutics 02/2024 - 04/2007
17	Glycemic Control 10/2022 - 06/2007
4	Injections 10/2021 - 01/2014
3	Bariatric Surgery 01/2021 - 09/2011
2	Secondary Prevention 01/2023 - 02/2006
2	Renal Replacement Therapy (Therapies, Renal Replacement) 10/2021 - 01/2021
2	Polypharmacy 01/2014 - 01/2012